To successfully refill a G&B toner cartridge, you must change the cartridge chipset. If you attempt to refill the cartridge without changing the chipset, you will still see the error message indicating that the cartridge is out of toner. This occurs because the chipset plays a crucial role in communicating the toner level to the printer. Therefore, for optimal performance and to avoid error messages, it is essential to always ensure that the chipset is replaced during the refilling process.